Glucose deprivation-induced disulfidptosis in human nucleus pulposus cells: a novel pathological mechanism of intervertebral disc degeneration

Abstract Background Limited supply of certain nutrients and deregulation of nucleus pulposus (NP) plays a key role in the pathogenesis of intervertebral disc degeneration (IVDD).However, whether nutrient deprivation-induced cell death, particularly disulfidptosis, contributes to the depletion of NP cells and the development of IVDD, is unknown.Meth

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Real Exchange Rate Misalignment and Economic Fundamentals in Korea

This study analyzes the response of economic fundamentals to a misalignment shock of the real effective exchange rate in Korea.The estimation results of the equilibrium exchange rate determination model and time series model show that there is no significant difference in the direction of the deviation from equilibrium and acupatch that the won is

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